Spectroscopy is an essential tool across many fields of science and industry. Techniques such as FTIR (Fourier Transform Infrared), NIR (Near-Infrared), and UV-Vis (Ultraviolet-Visible) spectroscopy provide valuable insights into the molecular structure and composition of materials.
At the heart of these methods are spectroscopy transmission cells, which hold the sample in the path of the spectrometer beam. The right choice of cell is crucial: it directly affects the quality, accuracy, and reproducibility of your measurements. Whether you’re analyzing liquids, gases, solids, or semi-solids, the proper cell selection ensures optimal pathlength, temperature control, chemical compatibility, and sample integrity.
In this guide, we’ll cover the main types of spectroscopy cells, explain how to choose the right one for your application, and share tips for maintenance and customization options.
Spectroscopy cells come in many forms, designed for specific sample types and analytical goals. The categories below give an overview of the most widely used configurations.
Liquid transmission cells are essential for FTIR, NIR, and UV-Vis analysis of liquid samples. The Pearl is most innovative and easiest to use transmission spectroscopy accessory that makes liquid, semi-liquid, mull and smear transmission sampling faster and more reliable than ever before.
Video: Pearl Liquids and Semi-Solids Transmission FTIR AccessoryGas-phase analysis often requires longer optical pathlengths to detect low-concentration species. Gas cells are available in various designs:
Transmission cells and cuvettes for UV-Vis-NIR applications come in a variety of pathlengths and materials (optical glass, IR quartz, UV quartz, sapphire, etc.) for compatibility with different acidic, neutral, and basic samples as well as spectral wavelength ranges. They’re used across life sciences, pharmaceuticals, and chemical analysis.
Selecting the proper cell depends on a combination of sample type, measurement goals, and practical considerations. Here are the key factors:
| Factor | Why It Matters |
|---|---|
| Material compatibility | Choose window and body materials resistant to your sample (solvents, acids, bases). |
| Pathlength | Shorter pathlengths for concentrated samples; longer for dilute solutions or gases. |
| Temperature range | Heated or cooled cells prevent condensation and support temperature-dependent studies. |
| Pressure tolerance | High-pressure cells required for pressurized or supercritical samples. |
| RoHS compliance | Important for regulated industries needing eco-friendly, compliant equipment. |
| Automation readiness | Flow-through cells integrate with automated systems for high-throughput analysis. |
If you’re unsure which model fits your needs, REFLEX Analytical can guide you to the right solution.
When off-the-shelf cells aren’t enough, REFLEX Analytical specializes in custom designs, including:
If your project requires something unique, our engineers can assist with design, prototyping, and production.
What is a spectroscopy cell?
A spectroscopy cell holds a sample in the path of the spectrometer beam to enable optical measurement.
What pathlength should I use?
It depends on your sample concentration: longer pathlengths are better for dilute samples; shorter for highly absorbing ones.
How do I clean my cell?
Use compatible solvents and avoid harsh chemicals or abrasives. Follow product-specific instructions.
Can I use the same cell for multiple techniques?
Some cells are versatile; others are optimized for specific wavelength ranges or techniques. Consult REFLEX for guidance.
Does REFLEX offer RoHS-compliant cells?
Yes, we offer a full line of RoHS-compliant sealed and flow-through cells.
Need help selecting the perfect spectroscopy cell?
Contact REFLEX Analytical to discuss your application.
